CHO PhotoScreen® P2RX1 Cell Line from PerkinElmer - USA

CHO PhotoScreen® P2RX1 Cell Line

Product number:   AX-009-PCF

Unit price:  This product is not available for online purchase.

Unit size:  1/EA

CHO PhotoScreen® cell line co-expressing the human P2X purinoceptor 1 (P2X1) ATP-gated cation channel and the photoprotein Photina® for flash-luminescence assays. The kit contains two vials of cryopreserved CHO PhotoScreen P2RX1 cells. The technical data sheet includes detailed cell line information as well as culture conditions and a protocol for the LumiLux® Cellular Screening Platform. The CHO PhotoScreen P2RX1 cell line has also been validated on the FLIPRTETRA® system.

The P2X1 cation channel is involved in a number of therapeutic areas including control of the lower genitourinary tract function (male fertility, urinary bladder, prostatic hyperplasia), vaso-constriction, inflammation and thrombosis.

Please inquire at your local sales office for more information. Terms and conditions apply.

FLIPRTETRA is a registered trademark of MDS Analytical Technologies.

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Features/ Benefits

  • Functional, homogenous and generic assay platform for calcium channels
  • Fully automatable and miniaturizable
  • Enables reduction in reagents and consumable costs
  • High signal to background ratio enabling detection of agonists, antagonists and allosteric modulators
  • Robust assay (Z, CV values, solvent resistance)
  • Reduces the number of false positives from autofluorescent compounds in screening libraries

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