FAQ

Specifications

Features

Standard Features

The 307 Sample Oxidizer is an automatic preparation and oxidization system for both single and dual radiolabeled samples containing ³H and/or ¹⁴C for use in liquid scintillation counting. The 307 Sample Oxidizer ensures reliable combustion of biological, environmental and industrial samples. This system includes the following standard features and benefits:

• Single “push button” operation initiates automatic cycle, positioning of vials and ignition basket, non-catalytic combustion, dispensing of scintillation cocktails and carbon dioxide trapping agent, and system cleaning.
• Physical separation of ³H and ¹⁴C radionuclides from dual labeled sample material for ease of sample analysis.
• Minimizes optical and chemical quenching. Reduces chemiluminescence in most sample preparations, increases statistical accuracy of liquid scintillation counting results. Eliminates self-absorption.
• Observation of combustion allows for visual inspection during sample burn.
• Complete combustion of liquid, wet or dry sample eliminates the need for chemical solubilization.
• Ensures maximum radionuclide recovery for ¹⁴C with sample size equivalent up to 40 millimoles of carbon dioxide and up to 85 millimoles of water for samples containing ³H (up to 1.5 grams).
• Radionuclide recovery for both ³H and ¹⁴C of >97% maximizes radionuclide separation for single label analysis using liquid scintillation counting techniques and an efficiency quench correlation curve for each radionuclide.
• Radionuclide memory of less than 0.08% for most ³H and ¹⁴C labeled sample materials.
• Non-catalytic combustion eliminates catalyst usage, cost and replacement.
• Accommodates 20 mL glass or low cost polyethylene vials.
• Capacity to process up to 60 samples per hour for each radionuclide.
• Unique design bellows-type reagent metering pumps.
• Pumps adjustable from 0 to 18 milliliters, automatically dispense accurate volumes of both ³H and ¹⁴C scintillation cocktails and carbon dioxide trapping agent.
• Long life, removable platinum ignition basket.
• Non-pressurized reagent storage tank capacity of five liters for each reagent allows up to 500 sample combustions between refills.
• Ambient temperature trapping of water and carbon dioxide provides safe and clean operation.
• Accessory kit with spare parts; included are additional O-rings, glass combustion flask, wrench, seals, and assorted small parts.

Additional Features

• A pressurized five liter, distilled water reservoir is provided for the automatic cleaning, steam injection, and pre-coating of the ³H exchange column.
• The distilled water reservoir has a vent valve for depressurizing the tank when the system is turned off, or when checking the distilled water level with the dipstick.
• The system has built-in pressure regulators and filters for nitrogen, oxygen, and water.
• A specially constructed reaction column eliminates loss of carbon dioxide absorber.
• A “reset button” to reset the combustion timer prior to “restart” of the program while the sample is still burning.
• “Override” button to cut off excessive combustion time after combustion has been completed.
• A “backpressure” indication gauge to monitor pressure in the trapping device during combustion.
• A “Test/Run” toggle valve. In the “Test” mode the entire system will be checked for leak tightness. Normal operation is in the “Run” mode.