Tyramide Signal Amplification (TSA) Systems

Tyramide Signal Amplification (TSA™) is a patented technology that amplifies both chromogenic and fluorescent signals in standard immunohistochemistry protocols. The result is a significant increase in sensitivity, without loss of resolution or increase in background.

Because TSA is a signal amplification technology, it eliminates the need for target amplification (PCR) sometimes used in in situ PCR when low or single copy genes are present. By using TSA in immunohistochemistry applications, unamplified detection levels can be maintained while utilizing up to 1,000-fold less primary antibody.