Iodination with Iodogen Reagent, [¹²⁵I]- or [¹³¹I]-

Iodogen labeling is a solid phase oxidative method offered by PerkinElmer that is similar to the Chloramine-T method, but is generally considered to be milder, since the reaction takes place on the surface of the oxidant, minimizing exposure of the substrate.

Reference: Salacinzki, P.R.P., et al., Anal.Biochem. 117:136 (1981).